Finance Manager

Company name: ONA Therapeutics

Job location: Barcelona, Catalonia, Spain (Hybrid)

Company Description

Ona Therapeutics is a biotech company located in Barcelona (Parc Científic de Barcelona, PCB), focused on developing first-in-class antibody drug conjugates (ADCs) for advanced cancer treatment. By partnering with leading academics and clinicians, we identify novel therapeutic targets from the unique biology of treatment refractory advanced cancer patients, to provide effective new treatments for patients with no remaining alternatives.

Scope

We are building our finance function in-house and are looking for a Finance Manager to work directly with the CFO as a key partner in shaping and professionalizing the department. This is the first strategic finance hire and will play a central role in establishing the company’s financial infrastructure.

The role combines financial control, FP&A, and operational finance, with a strong focus on execution. You will take ownership of day-to-day finance operations — including accounting, reporting, and systems — while progressively implementing scalable processes, internal controls, and tools.

Working closely with the CFO, you will contribute to budgeting, forecasting, cash management, and grant tracking, while also supporting decision-making at leadership level. You will interact regularly with the COO, ensuring financial visibility and discipline across the organization.

This is a hands-on role for someone who thrives in building environments, takes ownership, and is motivated to grow into a broader leadership position as the function evolves.

Role & Responsibilities

Accounting & Close (Primary Ownership)

• Own and run the full day-to-day accounting function, with the objective of progressively bringing activities in-house
• Lead the monthly, quarterly, and year-end close processes with a high standard of accuracy and timeliness
• Take full ownership of accruals, including complex areas such as clinical trial accruals and purchase order accruals
• Prepare financial statements under Spanish GAAP and support IFRS reporting requirements
• Establish and implement accounting policies, SOPs, and internal controls from the ground up

Parc Cientific de Barcelona, Baldiri Reixac 10, 08028 Barcelona, Spain Confidential www.ona-therapeutics.com

• • Build, manage, and develop the accounting function over time (internal and external resources)

FP&A & Business Partnering

• Own the annual budgeting process and periodic reforecasting
• Prepare and analyze budget vs. actuals, ensuring clear visibility on performance and deviations
• Deliver regular financial reporting and materials for the CFO
• Support decision-making through financial analysis, scenario planning, and business insight
• Partner closely with operational teams, particularly clinical, to ensure accurate planning and cost tracking

Cash, Treasury & Runway Management

• Manage day-to-day banking operations and payment planning
• Support fundraising processes, including financial data preparation

Systems & Process Build-Out

• Lead the implementation of ERP and finance systems, including accounting and procurement capabilities
• Design and implement procurement processes, including approval workflows and controls
• Drive automation and continuous improvement across finance operations

Grants, R&D Incentives & Funding

• Own the financial management of public grants, soft loans, and R&D tax credits
• Ensure proper tracking, reporting, and compliance with all funding requirements
• Act as finance lead in the preparation, justification, and optimization of these funding sources

Tax, Audit & Compliance

• Coordinate with external advisors to ensure full compliance across tax filings (VAT, corporate tax, etc.)
• Lead the audit process (interim and year-end), ensuring a clean and efficient execution
• Prepare annual accounts and act as the main point of contact for auditors and advisors

Payroll & External Coordination

• Ensure payroll is accurately reflected in financial records, including reconciliation and accounting treatment
• Oversee payroll outputs produced by external providers, ensuring accuracy and consistency with HR-provided input and financial records.

Parc Cientific de Barcelona, Baldiri Reixac 10, 08028 Barcelona, Spain Confidential www.ona-therapeutics.com

• Act as a main point of contact for external accountants, tax advisors, auditors, and other financial partners

Qualifications & Skills

Experience & Background

• 5–8+ years of experience in finance, covering both accounting and FP&A responsibilities
• Experience in biotech, life sciences, or R&D-driven environment is preferred or ex Big4 audit firm.
• Background in a high-growth or scaling company, with exposure to building or transforming finance processes
• Experience working closely with senior leadership (CFO, CEO, or equivalent)
• Strong understanding of Spanish GAAP; exposure to IFRS is a plus

Technical Expertise

• Solid accounting foundation, including close processes, accruals, and financial statement preparation
• Experience managing complex accruals (ideally clinical trials, R&D, or project-based environments)
• Strong FP&A capabilities, including budgeting, forecasting, and variance analysis
• Familiarity with grants, R&D tax credits, or similar funding mechanisms is a plus
• Experience with ERP implementation or optimization; comfortable working with finance systems and driving automation NetSuite experience preferred.
• Good understanding of tax and compliance processes in coordination with external advisors

Skills

• Hands-on and execution-driven, with the ability to operate at both detail and strategic level
• Strong ownership and accountability; able to independently drive topics from start to finish
• Structured and detail-oriented, with high standards for accuracy and quality
• Builder mindset: motivated to create processes, implement systems, and improve ways of working
• Strong analytical skills with the ability to translate data into clear insights
• Excellent communication skills, with the ability to interact effectively with both finance and non-finance stakeholders
• Comfortable working in a dynamic, evolving environment with changing priorities

Parc Cientific de Barcelona, Baldiri Reixac 10, 08028 Barcelona, Spain Confidential www.ona-therapeutics.com

What we offer

• A work environment, culture and passionate team in the oncology sector.
• A unique opportunity to work in an innovative and dynamic environment.
• Internal benefits such as flexible remuneration, flexible working hours, events along the year…

To apply, please submit your CV and cover letter to hr@ona-therapeutics.com

We look forward to reviewing your application and discovering how your skills and experience align with our company’s needs.

Business Intelligence Analyst

Company name: ONA Therapeutics

Job location: Barcelona, Catalonia, Spain (Hybrid)

Company Description

Ona Therapeutics is a biotech company located in Barcelona (Parc Científic de Barcelona, PCB), focused on developing first-in-class antibody drug conjugates (ADCs) for advanced cancer treatment. By partnering with leading academics and clinicians, we identify novel therapeutic targets from the unique biology of treatment refractory advanced cancer patients, to provide effective new treatments for patients with no remaining alternatives.

Scope

We are looking for a Business Intelligence Analyst with a strong scientific background to support data-driven decision-making across our project portfolio and strategic initiatives.

This role sits at the intersection of science, data, and project strategy, supporting the Head of Project & Business Management in transforming complex biological, clinical, and industry data into structured insights that guide internal decision-making.

You will play a key role in strengthening how the company uses data to evaluate priorities, track programs, and understand the competitive landscape.

Role and Responsibilities

Business Intelligence & Data Analysis

• Develop a deep understanding of the biotech/pharma landscape, including competitors, modalities, and therapeutic trends
• Gather, structure, and analyse scientific, clinical, and regulatory data (clinical trials, publications, databases, etc.)
• Translate complex datasets into clear insights, summaries, and decision-support materials
• Support portfolio and project teams by providing data-driven insights for prioritisation and planning
• Contribute to the definition of key analytical frameworks and indicators for project and portfolio evaluation

Parc Cientific de Barcelona, Baldiri Reixac 10, 08028 Barcelona, Spain Confidential www.ona-therapeutics.com

• Support the Head of Project & Business Management in preparing data-driven analyses for internal decision-making

Strategic Insight & External Analysis

• Support evaluation of external opportunities (assets, indications, collaborations) through structured data analysis
• Contribute to competitive intelligence and landscape mapping
• Assist in preparing analytical inputs for strategic discussions and presentations

Scientific Integration

• Participate in internal scientific and project meetings
• Collaborate closely with R&D and project management teams to understand data needs
• Contribute to a data-driven culture across project execution and decision-making

Tools & Data Systems

• Support the structuring and maintenance of internal BI and project intelligence databases
• Work with scientific databases, literature sources, and internal data systems
• Contribute to improving how data is collected, structured, and visualised across projects

Qualifications Requirements

• PhD in relevant scientific fields (Biology, Biochemistry, Pharmacology, Biomedical Sciences, etc.) Relevant professional experience in business intelligence highly analytical roles within biotech, consulting, venture capital, or technology transfer, demonstrating strong ability to structure complex problems, interpret data-driven insights, and support evidence-based decision-making.
• Strong interest in biotech, data analysis, and project/portfolio decision-making
• Experience in oncology, immunology, drug-development or related

Skills

• Strong analytical, structured, and systematic mindset
• Excellent critical thinking and problem-solving abilities
• Data-driven with a hypothesis-oriented approach
• Ability to translate complex scientific and clinical data into clear, actionable insights
• Ability to simplify complex information and extract key messages
• Strong attention to detail and organizational skills
• Excellent communication and presentation skills
• Intellectual curiosity and proactive mindset
• Ownership mindset with the ability to work independently in a fast-paced environment

Parc Cientific de Barcelona, Baldiri Reixac 10, 08028 Barcelona, Spain Confidential www.ona-therapeutics.com

What we offer

• • A work environment, culture and passionate team in the oncology sector.
• • A unique opportunity to work in an innovative and dynamic environment.
• • Internal benefits such as flexible remuneration, flexible working hours, events along the year…

To apply, please submit your CV and cover letter to hr@ona-therapeutics.com

We look forward to reviewing your application and discovering how your skills and experience align with our company’s needs.